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A view on EGFR-targeted therapies from the oncogene-addiction perspective

Tumor cell growth and survival can often be impaired by inactivating a single oncogen– a phenomenon that has been called as “oncogene addiction.” It is in such scenarios that molecular targeted therapies may succeed. among known oncogenes, the epidermal growth factor receptor (EGFR) has become the t...

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Detalles Bibliográficos
Autores principales: Perez, Rolando, Crombet, Tania, de Leon, Joel, Moreno, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636470/
https://www.ncbi.nlm.nih.gov/pubmed/23637683
http://dx.doi.org/10.3389/fphar.2013.00053