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A Quantitative System Pharmacology Computer Model for Cognitive Deficits in Schizophrenia

Although the positive symptoms of schizophrenia are reasonably well-controlled by current antipsychotics, cognitive impairment remains largely unaddressed. The Matrics initiative lays out a regulatory path forward and a number of targets have been tested in the clinic, so far without much success. T...

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Detalles Bibliográficos
Autores principales: Geerts, H, Roberts, P, Spiros, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636495/
https://www.ncbi.nlm.nih.gov/pubmed/23887686
http://dx.doi.org/10.1038/psp.2013.12