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Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis
Type II endometrial cancer (EMCA) represents only 10% of all EMCAs, but accounts for 40% of EMCA-related mortality. Previous studies of human tumors have shown an association between Type II tumors and damaged telomeres. We hypothesized that the lack of murine Type II EMCA models is due to the extre...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636499/ https://www.ncbi.nlm.nih.gov/pubmed/22689059 http://dx.doi.org/10.1038/onc.2012.232 |