Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis

Type II endometrial cancer (EMCA) represents only 10% of all EMCAs, but accounts for 40% of EMCA-related mortality. Previous studies of human tumors have shown an association between Type II tumors and damaged telomeres. We hypothesized that the lack of murine Type II EMCA models is due to the extre...

Descripción completa

Detalles Bibliográficos
Autores principales: Akbay, E A, Peña, C G, Ruder, D, Michel, J A, Nakada, Y, Pathak, S, Multani, A S, Chang, S, Castrillon, D H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636499/
https://www.ncbi.nlm.nih.gov/pubmed/22689059
http://dx.doi.org/10.1038/onc.2012.232

Ejemplares similares

Ejemplares similares