Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From the Development of Lipotoxic Cardiomyopathy

Although diabetic cardiomyopathy is associated with enhanced intramyocardial triacylglycerol (TAG) levels, the role of TAG catabolizing enzymes in this process is unclear. Because the TAG hydrolase, adipose triglyceride lipase (ATGL), regulates baseline cardiac metabolism and function, we examined w...

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Detalles Bibliográficos
Autores principales: Pulinilkunnil, Thomas, Kienesberger, Petra C., Nagendran, Jeevan, Waller, Terri J., Young, Martin E., Kershaw, Erin E., Korbutt, Gregory, Haemmerle, Guenter, Zechner, Rudolf, Dyck, Jason R.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636613/
https://www.ncbi.nlm.nih.gov/pubmed/23349479
http://dx.doi.org/10.2337/db12-0927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636613/
https://www.ncbi.nlm.nih.gov/pubmed/23349479
http://dx.doi.org/10.2337/db12-0927

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