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Metabolic Signatures of Human Adipose Tissue Hypoxia in Obesity

Adipose tissue (AT) hypoxia has been proposed as the cause of obesity-related AT dysfunction, moving the tissue toward a proinflammatory phenotype. In humans, AT oxygenation has been assessed by expression of hypoxia-sensitive genes or direct assessment of O(2) tension; the obvious read out of hypox...

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Detalles Bibliográficos
Autores principales: Hodson, Leanne, Humphreys, Sandy M., Karpe, Fredrik, Frayn, Keith N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636615/
https://www.ncbi.nlm.nih.gov/pubmed/23274888
http://dx.doi.org/10.2337/db12-1032