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Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3Kγ-Akt-AS160 in Skeletal Muscle Cells

Skeletal muscle glucose uptake in response to exercise is preserved in insulin-resistant conditions, but the signals involved are debated. ATP is released from skeletal muscle by contractile activity and can autocrinely signal through purinergic receptors, and we hypothesized it may influence glucos...

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Detalles Bibliográficos
Autores principales: Osorio-Fuentealba, Cesar, Contreras-Ferrat, Ariel E., Altamirano, Francisco, Espinosa, Alejandra, Li, Qing, Niu, Wenyan, Lavandero, Sergio, Klip, Amira, Jaimovich, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636621/
https://www.ncbi.nlm.nih.gov/pubmed/23274898
http://dx.doi.org/10.2337/db12-1066