Thyroid Hormone Promotes Postnatal Rat Pancreatic β-Cell Development and Glucose-Responsive Insulin Secretion Through MAFA

Neonatal β cells do not secrete glucose-responsive insulin and are considered immature. We previously showed the transcription factor MAFA is key for the functional maturation of β cells, but the physiological regulators of this process are unknown. Here we show that postnatal rat β cells express th...

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Detalles Bibliográficos
Autores principales: Aguayo-Mazzucato, Cristina, Zavacki, Ann Marie, Marinelarena, Alejandra, Hollister-Lock, Jennifer, El Khattabi, Ilham, Marsili, Alessandro, Weir, Gordon C., Sharma, Arun, Larsen, P. Reed, Bonner-Weir, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636623/
https://www.ncbi.nlm.nih.gov/pubmed/23305647
http://dx.doi.org/10.2337/db12-0849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636623/
https://www.ncbi.nlm.nih.gov/pubmed/23305647
http://dx.doi.org/10.2337/db12-0849

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