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β-Cell–Specific Protein Kinase A Activation Enhances the Efficiency of Glucose Control by Increasing Acute-Phase Insulin Secretion

Acute insulin secretion determines the efficiency of glucose clearance. Moreover, impaired acute insulin release is characteristic of reduced glucose control in the prediabetic state. Incretin hormones, which increase β-cell cAMP, restore acute-phase insulin secretion and improve glucose control. To...

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Detalles Bibliográficos
Autores principales: Kaihara, Kelly A., Dickson, Lorna M., Jacobson, David A., Tamarina, Natalia, Roe, Michael W., Philipson, Louis H., Wicksteed, Barton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636652/
https://www.ncbi.nlm.nih.gov/pubmed/23349500
http://dx.doi.org/10.2337/db12-1013