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An Antedrug of the CXCL12 Neutraligand Blocks Experimental Allergic Asthma without Systemic Effect in Mice

The chemokine receptor CXCR4 and its chemokine CXCL12 are involved in normal tissue patterning but also in tumor cell growth and survival as well as in the recruitment of immune and inflammatory cells, as successfully demonstrated using agents that block either CXCL12 or CXCR4. In order to achieve s...

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Detalles Bibliográficos
Autores principales: Daubeuf, François, Hachet-Haas, Muriel, Gizzi, Patrick, Gasparik, Vincent, Bonnet, Dominique, Utard, Valérie, Hibert, Marcel, Frossard, Nelly, Galzi, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636874/
https://www.ncbi.nlm.nih.gov/pubmed/23449983
http://dx.doi.org/10.1074/jbc.M112.449348