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CAND1 controls in vivo dynamics of the Cullin 1-RING ubiquitin ligase repertoire

The combinatorial architecture of cullin 1-RING ubiquitin ligases (CRL1s), in which multiple F-box containing substrate receptors (FBPs) compete for access to CUL1, poses special challenges to assembling CRL1 complexes through high affinity protein interactions while maintaining the flexibility to d...

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Detalles Bibliográficos
Autores principales: Wu, Shuangding, Zhu, Wenhong, Nhan, Tina, Toth, Julia I., Petroski, Matthew D., Wolf, Dieter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637025/
https://www.ncbi.nlm.nih.gov/pubmed/23535663
http://dx.doi.org/10.1038/ncomms2636