Effect of famotidine on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor

BACKGROUND: Apixaban is an oral, selective, direct factor Xa inhibitor approved for thromboprophylaxis after orthopedic surgery and stroke prevention in patients with atrial fibrillation, and under development for treatment of venous thromboembolism. This study investigated the effect of a gastric a...

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Detalles Bibliográficos
Autores principales: Upreti, Vijay V, Song, Yan, Wang, Jessie, Byon, Wonkyung, Boyd, Rebecca A, Pursley, Janice M, LaCreta, Frank, Frost, Charles E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637032/
https://www.ncbi.nlm.nih.gov/pubmed/23637566
http://dx.doi.org/10.2147/CPAA.S41999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637032/
https://www.ncbi.nlm.nih.gov/pubmed/23637566
http://dx.doi.org/10.2147/CPAA.S41999

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