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Effect of famotidine on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor
BACKGROUND: Apixaban is an oral, selective, direct factor Xa inhibitor approved for thromboprophylaxis after orthopedic surgery and stroke prevention in patients with atrial fibrillation, and under development for treatment of venous thromboembolism. This study investigated the effect of a gastric a...
Autores principales: | Upreti, Vijay V, Song, Yan, Wang, Jessie, Byon, Wonkyung, Boyd, Rebecca A, Pursley, Janice M, LaCreta, Frank, Frost, Charles E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637032/ https://www.ncbi.nlm.nih.gov/pubmed/23637566 http://dx.doi.org/10.2147/CPAA.S41999 |
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