Heparanase induced by advanced glycation end products (AGEs) promotes macrophage migration involving RAGE and PI3K/AKT pathway

BACKGROUND: Advanced glycation end products (AGEs), inflammatory-associated macrophage migration and accumulation are crucial for initiation and progression of diabetic vascular complication. Enzymatic activity of heparanase (HPA) is implicated strongly in dissemination of metastatic tumor cells and...

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Detalles Bibliográficos
Autores principales: Qin, Qiaojing, Niu, Jianying, Wang, Zhaoxia, Xu, Wangjie, Qiao, Zhongdong, Gu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637127/
https://www.ncbi.nlm.nih.gov/pubmed/23442498
http://dx.doi.org/10.1186/1475-2840-12-37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637127/
https://www.ncbi.nlm.nih.gov/pubmed/23442498
http://dx.doi.org/10.1186/1475-2840-12-37

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