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Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress

BACKGROUND: FGF21 is a promising intervention therapy for metabolic diseases as fatty liver, obesity and diabetes. Recent results suggest that FGF21 is highly expressed in hepatocytes under metabolic stress caused by starvation, hepatosteatosis, obesity and diabetes. Hepatic FGF21 elicits metabolic...

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Detalles Bibliográficos
Autores principales: Yang, Chaofeng, Lu, Weiqin, Lin, Tao, You, Pan, Ye, Min, Huang, Yanqing, Jiang, Xianhan, Wang, Cong, Wang, Fen, Lee, Mong-Hong, Yeung, Sai-Ching J, Johnson, Randy L, Wei, Chongjuan, Tsai, Robert Y, Frazier, Marsha L, McKeehan, Wallace L, Luo, Yongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637159/
https://www.ncbi.nlm.nih.gov/pubmed/23590285
http://dx.doi.org/10.1186/1471-230X-13-67