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Li Fraumeni syndrome, cancer and senescence: a new hypothesis
Li Fraumeni Syndrome (LFS) is a rare autosomal dominant hereditary cancer syndrome characterized by germline mutations in the TP53 tumour suppressor gene. Sufferers are prone to early onset cancers, particularly sarcomas, adrenocortical carcinoma and breast cancer. Cells from LFS sufferers are known...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637189/ https://www.ncbi.nlm.nih.gov/pubmed/23587008 http://dx.doi.org/10.1186/1475-2867-13-35 |