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miR-411 is up-regulated in FSHD myoblasts and suppresses myogenic factors

BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant muscle disorder, which is linked to the contraction of the D4Z4 array at chromosome 4q35. Recent studies suggest that this shortening of the D4Z4 array leads to aberrant expression of double homeobox protein 4 (DUX4)...

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Detalles Bibliográficos
Autores principales: Harafuji, Naoe, Schneiderat, Peter, Walter, Maggie C, Chen, Yi-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637251/
https://www.ncbi.nlm.nih.gov/pubmed/23561550
http://dx.doi.org/10.1186/1750-1172-8-55