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Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases

BACKGROUND: Central nervous system (CNS) invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. We have recently demonstrated that B. abortus infects microglia and astrocytes, eliciting the production of a variety of pro-inflammatory cytokines which c...

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Detalles Bibliográficos
Autores principales: Miraglia, M Cruz, Scian, Romina, Samartino, Clara García, Barrionuevo, Paula, Rodriguez, Ana M, Ibañez, Andrés E, Coria, Lorena M, Velásquez, Lis N, Baldi, Pablo C, Cassataro, Juliana, Delpino, M Victoria, Giambartolomei, Guillermo H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637408/
https://www.ncbi.nlm.nih.gov/pubmed/23587438
http://dx.doi.org/10.1186/1742-2094-10-47