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Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases
BACKGROUND: Central nervous system (CNS) invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. We have recently demonstrated that B. abortus infects microglia and astrocytes, eliciting the production of a variety of pro-inflammatory cytokines which c...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637408/ https://www.ncbi.nlm.nih.gov/pubmed/23587438 http://dx.doi.org/10.1186/1742-2094-10-47 |