Inefficient TLR4/MD-2 Heterotetramerization by Monophosphoryl Lipid A

Synthetic forms of E. coli monophosphoryl lipid A (sMLA) weakly activate the MyD88 (myeloid differentiation primary response protein) branch of the bifurcated TLR4 (Toll-like receptor 4) signaling pathway, in contrast to diphosphoryl lipid A (sDLA), which is a strong activator of both branches of TL...

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Detalles Bibliográficos
Autores principales: Casella, Carolyn R., Mitchell, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637451/
https://www.ncbi.nlm.nih.gov/pubmed/23638128
http://dx.doi.org/10.1371/journal.pone.0062622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637451/
https://www.ncbi.nlm.nih.gov/pubmed/23638128
http://dx.doi.org/10.1371/journal.pone.0062622

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