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The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction

BACKGROUND: Insulin/insulin-like growth factor signalling (IIS) has been described as one of the major pathways involved in growth control and homeostasis in multicellular organisms. Whereas its core components are well established, less is known about the molecular functions of IIS regulators. The...

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Detalles Bibliográficos
Autores principales: Almudi, Isabel, Poernbacher, Ingrid, Hafen, Ernst, Stocker, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637499/
https://www.ncbi.nlm.nih.gov/pubmed/23590848
http://dx.doi.org/10.1186/1478-811X-11-26