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Gβγ-mediated activation of protein kinase D exhibits subunit specificity and requires Gβγ-responsive phospholipase Cβ isoforms

BACKGROUND: Protein kinase D (PKD) constitutes a novel family of serine/threonine protein kinases implicated in fundamental biological activities including cell proliferation, survival, migration, and immune responses. Activation of PKD in these cellular activities has been linked to many extracellu...

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Detalles Bibliográficos
Autores principales: Lau, Winnie WI, Chan, Anthony SL, Poon, Lydia SW, Zhu, Jing, Wong, Yung H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637504/
https://www.ncbi.nlm.nih.gov/pubmed/23561540
http://dx.doi.org/10.1186/1478-811X-11-22