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Gβγ-mediated activation of protein kinase D exhibits subunit specificity and requires Gβγ-responsive phospholipase Cβ isoforms
BACKGROUND: Protein kinase D (PKD) constitutes a novel family of serine/threonine protein kinases implicated in fundamental biological activities including cell proliferation, survival, migration, and immune responses. Activation of PKD in these cellular activities has been linked to many extracellu...
Autores principales: | Lau, Winnie WI, Chan, Anthony SL, Poon, Lydia SW, Zhu, Jing, Wong, Yung H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637504/ https://www.ncbi.nlm.nih.gov/pubmed/23561540 http://dx.doi.org/10.1186/1478-811X-11-22 |
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