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Hirsutanol A, a novel sesquiterpene compound from fungus Chondrostereum sp., induces apoptosis and inhibits tumor growth through mitochondrial-independent ROS production: Hirsutanol A inhibits tumor growth through ROS production

BACKGROUND: Hirsutanol A is a novel sesquiterpene compound purified from fungus Chondrostereum sp. in Sarcophyton tortuosum. Our previous studies had demonstrated that hirsutanol A exhibited potent cytotoxic effect on many kinds of cancer cell lines. In the current study, the antitumor activity of h...

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Detalles Bibliográficos
Autores principales: Yang, Fen, Chen, Wen-Dan, Deng, Rong, Zhang, Hui, Tang, Jun, Wu, Ke-Wei, Li, Dan-Dan, Feng, Gong-Kan, Lan, Wen-Jian, Li, Hou-Jin, Zhu, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637523/
https://www.ncbi.nlm.nih.gov/pubmed/23394457
http://dx.doi.org/10.1186/1479-5876-11-32