Microbial transformation of anti-cancer steroid exemestane and cytotoxicity of its metabolites against cancer cell lines

BACKGROUND: Microbial transformation of steroids has been extensively used for the synthesis of steroidal drugs, that often yield novel analogues, not easy to obtain by chemical synthesis. We report here fungal transformation of a synthetic steroidal drug, exemestane, used for the treatment of breas...

Descripción completa

Detalles Bibliográficos
Autores principales: Baydoun, Elias, Bibi, Marium, Iqbal, Muhammad Asif, Wahab, Atia-tul, Farran, Dina, Smith, Colon, Sattar, Samina A, Rahman, Atta-ur, Choudhary, M Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637571/
https://www.ncbi.nlm.nih.gov/pubmed/23537428
http://dx.doi.org/10.1186/1752-153X-7-57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637571/
https://www.ncbi.nlm.nih.gov/pubmed/23537428
http://dx.doi.org/10.1186/1752-153X-7-57

Ejemplares similares