Codon pairs of the HIV-1 vif gene correlate with CD4+ T cell count

BACKGROUND: The human APOBEC3G (A3G) protein activity is associated with innate immunity against HIV-1 by inducing high rates of guanosines to adenosines (G-to-A) mutations (viz., hypermutation) in the viral DNA. If hypermutation is not enough to disrupt the reading frames of viral genes, it may lik...

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Detalles Bibliográficos
Autores principales: Bizinoto, Maria Clara, Yabe, Shiori, Leal, Élcio, Kishino, Hirohisa, Martins, Leonardo de Oliveira, de Lima, Mariana Leão, Morais, Edsel Renata, Diaz, Ricardo Sobhie, Janini, Luiz Mário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637627/
https://www.ncbi.nlm.nih.gov/pubmed/23578255
http://dx.doi.org/10.1186/1471-2334-13-173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637627/
https://www.ncbi.nlm.nih.gov/pubmed/23578255
http://dx.doi.org/10.1186/1471-2334-13-173

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