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Codon pairs of the HIV-1 vif gene correlate with CD4+ T cell count
BACKGROUND: The human APOBEC3G (A3G) protein activity is associated with innate immunity against HIV-1 by inducing high rates of guanosines to adenosines (G-to-A) mutations (viz., hypermutation) in the viral DNA. If hypermutation is not enough to disrupt the reading frames of viral genes, it may lik...
Autores principales: | Bizinoto, Maria Clara, Yabe, Shiori, Leal, Élcio, Kishino, Hirohisa, Martins, Leonardo de Oliveira, de Lima, Mariana Leão, Morais, Edsel Renata, Diaz, Ricardo Sobhie, Janini, Luiz Mário |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637627/ https://www.ncbi.nlm.nih.gov/pubmed/23578255 http://dx.doi.org/10.1186/1471-2334-13-173 |
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