Stop Antibiotics on guidance of Procalcitonin Study (SAPS): a randomised prospective multicenter investigator-initiated trial to analyse whether daily measurements of procalcitonin versus a standard-of-care approach can safely shorten antibiotic duration in intensive care unit patients - calculated sample size: 1816 patients

BACKGROUND: Unnecessary long-term use of broad-spectrum antibiotics is linked to the emergence and selection of resistant bacteria, prolonged hospitalisation and increased costs. Several clinical trials indicate that the biomarker procalcitonin (PCT) can guide antibiotic therapy. Some of these trial...

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Detalles Bibliográficos
Autores principales: Assink-de Jong, Evelien, de Lange, Dylan W, van Oers, Jos A, Nijsten, Maarten W, Twisk, Jos W, Beishuizen, Albertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637799/
https://www.ncbi.nlm.nih.gov/pubmed/23590389
http://dx.doi.org/10.1186/1471-2334-13-178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637799/
https://www.ncbi.nlm.nih.gov/pubmed/23590389
http://dx.doi.org/10.1186/1471-2334-13-178

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