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Systemically administered liposome-encapsulated Ad-PEDF potentiates the anti-cancer effects in mouse lung metastasis melanoma

BACKGROUND: The use of adenoviral vector for gene therapy is still an important strategy for advanced cancers, however, the lack of the requisite coxsackie-adenovirus receptor in cancer cells and host immune response to adenovirus limit the application of adenoviral vector in vivo. METHOD: We design...

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Detalles Bibliográficos
Autores principales: Shi, Hua-shan, Yang, Li-ping, Wei, Wei, Su, Xiao-qing, Li, Xiao-peng, Li, Meng, Luo, Shun-tao, Zhang, Hai-long, Lu, Lian, Mao, Yong-qiu, Kan, Bing, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637821/
https://www.ncbi.nlm.nih.gov/pubmed/23552524
http://dx.doi.org/10.1186/1479-5876-11-86