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Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use

A hallmark of addiction is the loss of control over drug intake, which is seen only in a fraction of those exposed to stimulant drugs like cocaine. The cellular mechanisms underlying vulnerability or resistance to compulsive drug use are still unknown. Here we show that individual variability in the...

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Detalles Bibliográficos
Autores principales: Bock, Roland, Shin, J. Hoon, Kaplan, Alanna R., Dobi, Alice, Markey, Eric, Kramer, Paul F., Gremel, Christina M., Christensen, Christine H., Adrover, Martin F., Alvarez, Veronica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637872/
https://www.ncbi.nlm.nih.gov/pubmed/23542690
http://dx.doi.org/10.1038/nn.3369