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Versatile synthesis of probes for high-throughput enzyme activity screening
Mass spectrometry based technologies are promising as generalizable high-throughput assays for enzymatic activity. In one such technology, a specialized enzyme substrate probe is presented to a biological mixture potentially exhibiting enzymatic activity, followed by an in situ enrichment step using...
Autores principales: | de Rond, Tristan, Peralta-Yahya, Pamela, Cheng, Xiaoliang, Northen, Trent R., Keasling, Jay D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637890/ https://www.ncbi.nlm.nih.gov/pubmed/23568610 http://dx.doi.org/10.1007/s00216-013-6888-z |
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