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DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon–intron structure

DNA methylation is known to regulate transcription and was recently found to be involved in exon recognition via cotranscriptional splicing. We recently observed that exon–intron architectures can be grouped into two classes: one with higher GC content in exons compared to the flanking introns, and...

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Detalles Bibliográficos
Autores principales: Gelfman, Sahar, Cohen, Noa, Yearim, Ahuvi, Ast, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638135/
https://www.ncbi.nlm.nih.gov/pubmed/23502848
http://dx.doi.org/10.1101/gr.143503.112