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DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon–intron structure
DNA methylation is known to regulate transcription and was recently found to be involved in exon recognition via cotranscriptional splicing. We recently observed that exon–intron architectures can be grouped into two classes: one with higher GC content in exons compared to the flanking introns, and...
Autores principales: | Gelfman, Sahar, Cohen, Noa, Yearim, Ahuvi, Ast, Gil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638135/ https://www.ncbi.nlm.nih.gov/pubmed/23502848 http://dx.doi.org/10.1101/gr.143503.112 |
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