Sequencing of isolated sperm cells for direct haplotyping of a human genome

There is increasing evidence that the phenotypic effects of genomic sequence variants are best understood in terms of variant haplotypes rather than as isolated polymorphisms. Haplotype analysis is also critically important for uncovering population histories and for the study of evolutionary geneti...

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Detalles Bibliográficos
Autores principales: Kirkness, Ewen F., Grindberg, Rashel V., Yee-Greenbaum, Joyclyn, Marshall, Christian R., Scherer, Stephen W., Lasken, Roger S., Venter, J. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638138/
https://www.ncbi.nlm.nih.gov/pubmed/23282328
http://dx.doi.org/10.1101/gr.144600.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638138/
https://www.ncbi.nlm.nih.gov/pubmed/23282328
http://dx.doi.org/10.1101/gr.144600.112

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