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PRISM offers a comprehensive genomic approach to transcription factor function prediction

The human genome encodes 1500–2000 different transcription factors (TFs). ChIP-seq is revealing the global binding profiles of a fraction of TFs in a fraction of their biological contexts. These data show that the majority of TFs bind directly next to a large number of context-relevant target genes,...

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Detalles Bibliográficos
Autores principales: Wenger, Aaron M., Clarke, Shoa L., Guturu, Harendra, Chen, Jenny, Schaar, Bruce T., McLean, Cory Y., Bejerano, Gill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638144/
https://www.ncbi.nlm.nih.gov/pubmed/23382538
http://dx.doi.org/10.1101/gr.139071.112