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TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2

TLR and complement activation ensures efficient clearance of infection. Previous studies documented synergism between TLRs and the receptor for the pro-inflammatory complement peptide C5a (C5aR/CD88), and regulation of TLR-induced pro-inflammatory responses by C5aR, suggesting crosstalk between TLRs...

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Detalles Bibliográficos
Autores principales: Raby, Anne-Catherine, Holst, Benjamin, Davies, James, Colmont, Chantal, Laumonnier, Yves, Coles, Barbara, Shah, Sanjoy, Hall, Judith, Topley, Nicholas, Köhl, Jörg, Morgan, B Paul, Labéta, Mario O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638321/
https://www.ncbi.nlm.nih.gov/pubmed/21630250
http://dx.doi.org/10.1002/eji.201041350