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TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2
TLR and complement activation ensures efficient clearance of infection. Previous studies documented synergism between TLRs and the receptor for the pro-inflammatory complement peptide C5a (C5aR/CD88), and regulation of TLR-induced pro-inflammatory responses by C5aR, suggesting crosstalk between TLRs...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638321/ https://www.ncbi.nlm.nih.gov/pubmed/21630250 http://dx.doi.org/10.1002/eji.201041350 |