The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability

CRYAB (αB-crystallin) is expressed in many tissues and yet the R120G mutation in CRYAB causes tissue-specific pathologies, namely cardiomyopathy and cataract. Here, we present evidence to demonstrate that there is a specific functional interaction of CRYAB with desmin intermediate filaments that pre...

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Detalles Bibliográficos
Autores principales: Elliott, Jayne L., Der Perng, Ming, Prescott, Alan R., Jansen, Karin A., Koenderink, Gijsje H., Quinlan, Roy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638400/
https://www.ncbi.nlm.nih.gov/pubmed/23530264
http://dx.doi.org/10.1098/rstb.2012.0375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638400/
https://www.ncbi.nlm.nih.gov/pubmed/23530264
http://dx.doi.org/10.1098/rstb.2012.0375

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