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Melatonin Suppresses the Expression of 45S Preribosomal RNA and Upstream Binding Factor and Enhances the Antitumor Activity of Puromycin in MDA-MB-231 Breast Cancer Cells

Since the dysregulation of ribosome biogenesis is closely associated with tumor progression, in the current study, the critical role of ribosome biogenesis related signaling was investigated in melatonin and/or puromycin induced apoptosis in MDA-MB-231 breast cancer cells. Despite its weak cytotoxic...

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Detalles Bibliográficos
Autores principales: Jung, Ji Hoon, Sohn, Eun Jung, Shin, Eun Ah, Lee, Duckgue, Kim, Bonglee, Jung, Deok-Beom, Kim, Ji-Hyun, Yun, Miyong, Lee, Hyo-Jeong, Park, Yong Koo, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638601/
https://www.ncbi.nlm.nih.gov/pubmed/23690862
http://dx.doi.org/10.1155/2013/879746