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Sulforaphane Attenuates Gentamicin-Induced Nephrotoxicity: Role of Mitochondrial Protection

Sulforaphane (SFN), an isothiocyanate naturally occurring in Cruciferae, induces cytoprotection in several tissues. Its protective effect has been associated with its ability to induce cytoprotective enzymes through an Nrf2-dependent pathway. Gentamicin (GM) is a widely used antibiotic; nephrotoxici...

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Detalles Bibliográficos
Autores principales: Negrette-Guzmán, Mario, Huerta-Yepez, Sara, Medina-Campos, Omar Noel, Zatarain-Barrón, Zyanya Lucía, Hernández-Pando, Rogelio, Torres, Ismael, Tapia, Edilia, Pedraza-Chaverri, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638608/
https://www.ncbi.nlm.nih.gov/pubmed/23662110
http://dx.doi.org/10.1155/2013/135314