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Sulforaphane Attenuates Gentamicin-Induced Nephrotoxicity: Role of Mitochondrial Protection
Sulforaphane (SFN), an isothiocyanate naturally occurring in Cruciferae, induces cytoprotection in several tissues. Its protective effect has been associated with its ability to induce cytoprotective enzymes through an Nrf2-dependent pathway. Gentamicin (GM) is a widely used antibiotic; nephrotoxici...
Autores principales: | Negrette-Guzmán, Mario, Huerta-Yepez, Sara, Medina-Campos, Omar Noel, Zatarain-Barrón, Zyanya Lucía, Hernández-Pando, Rogelio, Torres, Ismael, Tapia, Edilia, Pedraza-Chaverri, José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638608/ https://www.ncbi.nlm.nih.gov/pubmed/23662110 http://dx.doi.org/10.1155/2013/135314 |
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