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Molecular Mechanisms of Large-Conductance Ca(2+)-Activated Potassium Channel Activation by Ginseng Gintonin

Gintonin is a unique lysophosphatidic acid (LPA) receptor ligand found in Panax ginseng. Gintonin induces transient [Ca(2+)](i) through G protein-coupled LPA receptors. Large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels are expressed in blood vessels and neurons and play important roles in bl...

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Detalles Bibliográficos
Autores principales: Choi, S. H., Lee, B. H., Hwang, S. H., Kim, H. J., Lee, S. M., Kim, H. C., Rhim, H. W., Nah, S. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638619/
https://www.ncbi.nlm.nih.gov/pubmed/23662129
http://dx.doi.org/10.1155/2013/323709