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Pro-survival effect of Dock180 overexpression on rat-derived H9C2 cardiomyocytes

BACKGROUND: Integrin β1 subunit and its downstream molecule, focal adhesion kinase (FAK), have been demonstrated to be indispensible to the promotion of cell proliferation and survival and anti-apoptosis in cardiomyocytes via activation of their downstream pro-survival signaling molecule, AKT. As a...

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Detalles Bibliográficos
Autores principales: Yan, An, Li, Gang, Zhang, Xu, Zhu, Bingbao, Linghu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638688/
https://www.ncbi.nlm.nih.gov/pubmed/23314417
http://dx.doi.org/10.12659/MSMBR.883738