The failure of animal models of neuroprotection in acute ischemic stroke to translate to clinical efficacy

Summary The discrepancy in results regarding neuroprotective agents in animal experiments compared to clinical trials is a major problem. While many neuroprotective agents have been proven effective in a variety of animal ischemic stroke models, none have been shown to work in phase III clinical tri...

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Detalles Bibliográficos
Autores principales: Xu, Sui-yi, Pan, Su-yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2013
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638705/
https://www.ncbi.nlm.nih.gov/pubmed/23353570
http://dx.doi.org/10.12659/MSMBR.883750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638705/
https://www.ncbi.nlm.nih.gov/pubmed/23353570
http://dx.doi.org/10.12659/MSMBR.883750

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