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An analogue-sensitive approach identifies basal body rotation and flagellum attachment zone elongation as key functions of PLK in Trypanosoma brucei

Polo-like kinases are important regulators of cell division, playing diverse roles in mitosis and cytoskeletal inheritance. In the parasite Trypanosoma brucei, the single PLK homologue TbPLK is necessary for the assembly of a series of essential organelles that position and adhere the flagellum to t...

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Detalles Bibliográficos
Autores principales: Lozano-Núñez, Ana, Ikeda, Kyojiro N., Sauer, Thomas, de Graffenried, Christopher L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639044/
https://www.ncbi.nlm.nih.gov/pubmed/23447704
http://dx.doi.org/10.1091/mbc.E12-12-0846