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Suppression of STIM1 inhibits human glioblastoma cell proliferation and induces G0/G1 phase arrest
BACKGROUND: Depletion of calcium (Ca(2+)) from the endoplasmic reticulum (ER) activates the ubiquitous store-operated Ca(2+) entry (SOCE) pathway which sustains long-term Ca(2+) signals and is critical for cellular functions. Stromal interacting molecule 1 (STIM1) serves a dual role as an ER Ca(2+)...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639102/ https://www.ncbi.nlm.nih.gov/pubmed/23578185 http://dx.doi.org/10.1186/1756-9966-32-20 |