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Enhanced Production of Bovine Chymosin by Autophagy Deficiency in the Filamentous Fungus Aspergillus oryzae

Aspergillus oryzae has been utilized as a host for heterologous protein production because of its high protein secretory capacity and food-safety properties. However, A. oryzae often produces lower-than-expected yields of target heterologous proteins due to various underlying mechanisms, including d...

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Detalles Bibliográficos
Autores principales: Yoon, Jaewoo, Kikuma, Takashi, Maruyama, Jun-ichi, Kitamoto, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639164/
https://www.ncbi.nlm.nih.gov/pubmed/23658635
http://dx.doi.org/10.1371/journal.pone.0062512