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Enhanced Production of Bovine Chymosin by Autophagy Deficiency in the Filamentous Fungus Aspergillus oryzae
Aspergillus oryzae has been utilized as a host for heterologous protein production because of its high protein secretory capacity and food-safety properties. However, A. oryzae often produces lower-than-expected yields of target heterologous proteins due to various underlying mechanisms, including d...
Autores principales: | Yoon, Jaewoo, Kikuma, Takashi, Maruyama, Jun-ichi, Kitamoto, Katsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639164/ https://www.ncbi.nlm.nih.gov/pubmed/23658635 http://dx.doi.org/10.1371/journal.pone.0062512 |
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