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Identification of Residues of SARS-CoV nsp1 That Differentially Affect Inhibition of Gene Expression and Antiviral Signaling

An epidemic of Severe Acute Respiratory Syndrome (SARS) led to the identification of an associated coronavirus, SARS-CoV. This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and in...

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Detalles Bibliográficos
Autores principales: Jauregui, Andrew R., Savalia, Dhruti, Lowry, Virginia K., Farrell, Cara M., Wathelet, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639174/
https://www.ncbi.nlm.nih.gov/pubmed/23658627
http://dx.doi.org/10.1371/journal.pone.0062416