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HnRNP A1/A2 and SF2/ASF Regulate Alternative Splicing of Interferon Regulatory Factor-3 and Affect Immunomodulatory Functions in Human Non-Small Cell Lung Cancer Cells

Heterogeneous nuclear ribonucleoparticule A1/A2 (hnRNP A1/A2) and splicing factor 2/alternative splicing factor (SF2/ASF) are pivotal for precursor messenger RNA (pre-mRNA) splicing. Interferon regulatory factor-3 (IRF-3) plays critical roles in host defense against viral and microbial infection. Tr...

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Detalles Bibliográficos
Autores principales: Guo, Rong, Li, Yong, Ning, Jinying, Sun, Dan, Lin, Lianjun, Liu, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639176/
https://www.ncbi.nlm.nih.gov/pubmed/23658645
http://dx.doi.org/10.1371/journal.pone.0062729