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Complex Genetic Architecture of Cardiac Disease in a Wild Type Inbred Strain of Drosophila melanogaster

Natural populations of the fruit fly, Drosophila melanogaster, segregate genetic variation that leads to cardiac disease phenotypes. One nearly isogenic line from a North Carolina peach orchard, WE70, is shown to harbor two genetically distinct heart phenotypes: elevated incidence of arrhythmias, an...

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Detalles Bibliográficos
Autores principales: Zhang, Zhi, Hsieh, Benjamin, Poe, Amy, Anderson, Julie, Ocorr, Karen, Gibson, Greg, Bodmer, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639251/
https://www.ncbi.nlm.nih.gov/pubmed/23638165
http://dx.doi.org/10.1371/journal.pone.0062909