MicroRNA-146a Is Upregulated by and Negatively Regulates TLR2 Signaling

TLR signaling is a crucial component of the innate immune response to infection. MicroRNAs (miRNAs) have been shown to be upregulated during TLR signaling. Specifically, microRNA-146a (miR-146a) plays a key role in endotoxin tolerance by downregulating interleukin-1 receptor-associated kinase 1 (IRA...

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Detalles Bibliográficos
Autores principales: Quinn, Edel M., Wang, Jiang Huai, O’Callaghan, Grace, Redmond, H. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639252/
https://www.ncbi.nlm.nih.gov/pubmed/23638011
http://dx.doi.org/10.1371/journal.pone.0062232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639252/
https://www.ncbi.nlm.nih.gov/pubmed/23638011
http://dx.doi.org/10.1371/journal.pone.0062232

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